Quantification of the distribution of blood flow pressure with postures

At a different angle, this study analyzed the contour chart of blood flow pressure, extreme pressure and its position to quantify DBFP in thirteen different postures with gravity considered or not (G ≠ 0 or G = 0). The aim was to determine the suitable body positions, in which the postural model of a single vessel could be simplified to two-dimensional (2D) symmetrical one while only considering such factors as posture and gravity. Computational fluid dynamic simulations were performed. Numerical results demonstrated that the DBFP showed 2D axisymmetry at ±90 ̊ and three-dimensional (3D) asymmetry at any other posture with G ≠ 0, and 2D axisymmetrical one at any posture with G = 0. Therefore, modeling a vessel as a 2D model is feasible in space and at ±90 ̊ posture on earth. In addition, the maximum pressure occurred between the inlet and the middle of the vessel, and its position variation mainly happened in the range of 0 ̊ 15 ̊. For a single vessel, this study provides the first theoretical evidence for cardiovascular modeling in microgravity and may help guide the researchers in designing defense devices for astronauts or patients clinically.